Garnet
I have had good luck on on both Mac OS and Windows 10 computers and my VX6r with the cable I purchased from Mark Dunkle KJ6ZWL. His company is BlueMax49ers. Here’s a link to the one you need on Ebay.
https://www.ebay.com/itm/FTDI-USB-Programming-Cable-Yaesu-VX-6E-VX-6R-VX-7E-VX-7R-CT-91-/161733645426
Cheers and 73
Jim KJ6TRT