This bit might not be obvious; if your operating system recognizes the cable as a serial COM port device, that's all you need on the OS side. After that, it's a matter of telling CHIRP what radio and what COM port to use.
Steve
-- "Any sufficiently advanced technology is indistinguishable from magic." -- Clarke's Third Law
"Any technology distinguishable from magic is insufficiently advanced." -- Benford's Corollary
"Any sufficiently advanced magic is indistinguishable from technology." -- Charles Stross, Dead Lies Dreaming
“It's still magic even if you know how it's done.” -- Terry Pratchett