Yep, the driver issue is probably the biggest gotcha with these radios. Install the right driver, and all is fine. In my case, the driver installation for the UV-5R had a bonus side effect, it also enabled another USB-serial cable which I had kicking around to work (I'm not even sure where that cable came from!). :)I got mine working finally. I had to go back to http://www.miklor.com/uv5r/ and install the other driver. The cable that came with my UV-5R has the wrong driver. Once I got that done, Chirp works just fine.KD0WEH
-- 73 de Tony VK3JED/VK3IRL http://vkradio.com