First I would suggest trying out the latest daily. 
http://chirp.danplanet.com/projects/chirp/wiki/Download - scroll to bottom in "development builds" section

Second, for mac, if you have chinese cable, it's probably fake PL2303. The official mac driver might look like its working, but nothing really happens. (At least on windows, you get the yellow icon and code 10.)
You will probably want to try out the fixed driver: http://changux.co/osx-installer-to-pl2303-serial-usb-on-osx-lio/

Thirdly, with the chinese radios, sometimes they need to be factory reset to work properly. I suggest taking a backup w/ "good" oem software, then resetting radio, then attempting to download that "default" image into chirp.

If the cable works on windows w/ oem software, but does not work with same cable on windows w/ latest daily chirp, then there may be a bug with chirp and your radio. In that case, please follow this guide and open a bug:
http://chirp.danplanet.com/projects/chirp/wiki/How_to_report_issues
 
  On Saturday, November 16, 2013 12:51 PM, David M. Carney <n1zhe.nh@gmail.com> wrote:
  
    OK, I'm using the latest Stable release (not the daily) on all three
    machines.

    The cable, though it appears to be recognized by Chirp does not
    work. When I say "recognized", I mean Chirp seems to be
    downloading/uploading when I tell it to but no data is actually
    transferred either way.

    The light falshes on the radio as it does with the TYT software but
    no data is actually transferred.

On 11/16/2013 01:44 PM, Jens J. wrote:

Sorry David,
I'm
            still not quite following.

Are you
          saying the cable works ok with stock programming software on
          windows, but will not work with chirp on windows?
If so, can
          you confirm you are using the latest daily release of chirp?

If this is
          not so, please be explicit with where this is working and
          where this is not working, to include which OS and programming
          software you are using for each combination. 

  On Saturday,
                  November 16, 2013 12:34 PM, David M. Carney
                  <n1zhe.nh@gmail.com> wrote:

 I have Windows 7, a late 2007 iMac or an Ubuntu
                    13.10 machine to choose from.

                    The cable works as expected on my Windows 7 machine
                    and it seems to be detected by my Mac and Linux
                    (using the "dmesg | grep tty" command from a
                    terminal.

                    While useful, the "stock" programming software
                    leaves a LOT to be desired.

On
                        11/16/2013 01:16 PM, Jens J. wrote:

You did not mention if you are on
                              windows or mac?
If on Windows, are you able to use
                            the OEM programming software with said cable
                            without any issues?

  On Saturday, November 16,
                                    2013 12:12 PM, David M. Carney <n1zhe.nh@gmail.com>
                                    wrote:

As
                                  many others may have discovered, the
                                  "stock" programming cable does 

                                  not work with Chirp. The program acts
                                  like it's downloading from the 

                                  radio, I get the progress bar, etc,
                                  but then there is nothing in Chirp. 

                                  Just a blank page in Chirp for my
                                  radio.

                                  I know the problem lies with the
                                  Prolific chipset.

                                  So I'm curious, what are other users
                                  who use this radio use for a cable?

                                  David

_______________________________________________

                                  chirp_users mailing list

                                  chirp_users@intrepid.danplanet.com

                                  http://intrepid.danplanet.com/mailman/listinfo/chirp_users

_______________________________________________
chirp_users mailing list
chirp_users@intrepid.danplanet.com
http://intrepid.danplanet.com/mailman/listinfo/chirp_users