UPDATE:

The cable appears to be fine.  I installed Kenwood's MCP-1A software and it downloaded the radio fine, and all 43 channels appear in the software.

When I turned off the radio, unplugged the cable from the fromputer, then replugged the cable into the computer and turned on the radio, the First time I tried to download the radio I get just a blank screen. 

After waiting 30 seconds with nothing happening, and without unplugging or turning off the radio, I tried again to download the radio, then I get the message

could not open port COM4: [Error 5] Access is denied.

======================================================

I am trying to program my Kenwood TM281 for the first time. I'm using Windows 10.  I previously ran Chirp to program a Wouxon hand held and it worked fine with that cable.

I have a Prolific cable I got from BlueMax49ers.   The instructions said it was a genuine Prolific chip and to use the latest drivers.  So I checked and it is using the latest drivers (3.8.28.0).  When I started Chirp, I plugged in the radio, and selected "Download from Radio".   It gave me a dialog with Com3 preselected, and I selected Kenwood and TM281. When I clicked OK in the dialog, I get this message:

An ERROR Has Occurred
could not open port COM4: [Error 5] Access is denied.

I tried Com3, and got the same error. 

An ERROR Has Occurred
could not open port COM3: [Error2] The System Cannot find The File specified.

(this may be the original error, I don't know. I changed the com port to Com4 before writing down what the original error was when it originally went to Com3)

I looked into Device Manager, and under Ports (Com and LPT) It says the Prolific USB to Serial Comm Port (Com4)

I looked at the Properties and it says this:

Does this sound familiar?

Steve

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