It works with mine.  The trick is that you need to download and install an older driver.

Here is an overview. http://www.miklor.com/COM/UV_Drivers.php#install

-jkg/KB3KKY

From: chirp_users-bounces@intrepid.danplanet.com [mailto:chirp_users-bounces@intrepid.danplanet.com] On Behalf Of Rafael Yerushalmi
Sent: Monday, October 28, 2013 9:17 AM
To: chirp_users@intrepid.danplanet.com
Subject: [chirp_users] UV-B6 ???

Hello there.

I bougnt this new UVB6 baeofeng.

does the CHRIP support it ???

--
Best wishess for you !!! ( :

Y  Rafael